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  • What is the RadTox™ test and how does it work?
    RadTox™ is a liquid biopsy test that quantifies circulating cell-free DNA (cfDNA) levels in plasma to monitor cancer treatment response and prognosis, using proprietary isobDNA™ technology.
  • What are the main advantages of the RadTox™ test over other liquid biopsy tests of the same indications?
    Key advantages include pan-cancer applicability, earlier detection of treatment response than imaging, small sample requirement, cost-effectiveness, and rapid turnaround time.
  • How does the RadTox™ test complement imaging and other diagnostic tests?
    RadTox™ provides real-time insights into tumor dynamics and treatment response, often earlier than imaging, and complements imaging and tissue biopsies for comprehensive monitoring.
  • Is RadTox™ ready for clinical use and covered by insurance?
    Yes, RadTox™ is a CLIA-certified LDT, and is covered by Medicare and some private insurers starting January 2024.
  • For which cancer types is the RadTox™ test suitable?
    RadTox™ test is a pan-cancer test suitable for monitoring treatment responses and tumor recurrence across all solid tumor types and stages, without the need for prior tumor genomic profiling.
  • How frequently can the RadTox™ test be performed?
    RadTox™ can be performed as frequently as weekly or biweekly during active treatment, and monthly during surveillance, enabling continuous monitoring.
  • What is the turnaround time for RadTox™ test results?
    The RadTox™ test has a rapid turnaround time of approximately 5-7 days, facilitating timely clinical decision-making.
  • How does the RadTox test compare to ctDNA (circulating tumor DNA) tests?
    While ctDNA tests provide genomic insights, RadTox™ quantifies total cfDNA levels, offering a complementary perspective on tumor burden and treatment response.
  • Can the RadTox™ test predict treatment outcomes or prognosis?
    Yes, studies show that baseline cfDNA levels and changes during treatment can be prognostic for outcomes like overall survival and progression-free survival.
  • How sensitive is the RadTox™ test in detecting molecular residual disease or tumor recurrence?
    RadTox™ can detect significant increases in cfDNA levels that may indicate molecular residual disease (MRD) or tumor recurrence, often earlier than imaging or conventional biomarkers.
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